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Diablo 4 Rune Crafting Recipes & How to Craft Ancestral Mythic Unique Items

10/5/2024 3:00:10 PM

Crafting is one of the ways to get specific items in Diablo IV, with the addition of various runes, players are allowed to use runes to craft powerful Mythic Uniques. In this article, we’ll list rune crafting recipes for all Ancestral Mythic Unique items and better runes in Diablo 4, including the new items added in Season 6 or Vessel of Hatred.

Related Read: Best Way to Farm Runes in Diablo 4


Updated (October 9, 2024):

Diablo 4 Rune Crafting Recipes & Materials in Vessel of Hatred

The game is about to undergo a significant transformation with the introduction of rune crafting in Diablo 4 DLC. Runes are only available for players who purchased the Vessel of Hatred DLC. One of the most exciting applications of rune crafting is in the creation of Mythic (Uber) Unique items. Previously, these ultra-rare items required four Resplendent Sparks to craft. The new system offers an alternative method. 


D4 Mythic Unique Crafting Recipes

To craft a Mythic Unique in Diablo 4 Season 6 or Vessel of Hatred, you’ll need a specific number of Resplendent Sparks and potentially some runes (legendary runes, rare runes & magic runes). This chart also covers four new S6 Ancestral Mythic Unique items to be added for the VoH expansion, including Heir of Perdition (Ancestral Mythic Unique Helm), Shattered Vow (Ancestral Mythic Unique Polearm), Shroud of False Death (Ancestral Mythic Unique Chest Armor), and Nesēkēm, the Herald (Ancestral Mythic Unique Glaive) is exclusive to the new class - Spiritborn.

Item NameRecipe
Ring of Starless SkiesResplendent Spark x2, Ohm x6, Tzic x6, Cem x6
Heir of PerditionResplendent Spark x2, Jah x6, Que x6, Gar x6
Harlequin CrestResplendent Spark x2, Eom x6, Lac x6, Ton x6
Andariel's VisageResplendent Spark x2, Tam x6, Qax x6, Zan x6
Tyrael's MightResplendent Spark x2, Lith x6, Feo x6, Tec x6
Shroud of False DeathResplendent Spark x2, Bac x6, Kry x6, Moni x6
Melted Heart of SeligResplendent Spark x2, Vex x6, Thul x6, Tun x6
The GrandfatherResplendent Spark x2, Xol x6, Kaa x6, Yax x6
Ahavarion, Spear of LycanderResplendent Spark x2, Yom x6, Poc x6, Cir x6
Shattered VowResplendent Spark x2, Xan x6, Ner x6, Teb x6
DoombringerResplendent Spark x2, Ahu x6, Neo x6, Lum x6
Nesēkēm, the HeraldResplendent Spark x2, Yul x6, Wat x6, Tal x6


D4 Higher-Rarity Rune Crafting Recipes

For players looking to expand their rune collection or hunt for specific powerful runes, the system offers a way to combine lower-tier runes for a chance at higher-quality ones

Rune TypeRecipe
Random Rare or Legendary RuneZec x3
Random Rare or Legendary RuneWat x3
Random Rare or Legendary RuneTzic x3
Random Rare or Legendary RuneThul x3
Random Rare or Legendary RuneTeb x3
Random Rare or Legendary RuneQue x3
Random Rare or Legendary RunePoc x3
Random Rare or Legendary RuneNer x3
Random Rare or Legendary RuneNeo x3
Random Rare or Legendary RuneMot x3
Random Rare or Legendary RuneLith x3
Random Rare or Legendary RuneLac x3
Random Rare or Legendary RuneKry x3
Random Rare or Legendary RuneKaa x3
Random Rare or Legendary RuneJah x3
Random Rare or Legendary RuneFeo x3
Random Rare or Legendary RuneCeh x3
Random Magic or Rare RuneZan x3
Random Magic or Rare RuneYax x3
Random Magic or Rare RuneUr x3
Random Magic or Rare RuneTun x3
Random Magic or Rare RuneTon x3
Random Magic or Rare RuneTec x3
Random Magic or Rare RuneTam x3
Random Magic or Rare RuneTal x3
Random Magic or Rare RuneQua x3
Random Magic or Rare RuneQax x3
Random Magic or Rare RuneOno x3
Random Magic or Rare RuneMet x3
Random Magic or Rare RuneLum x3
Random Magic or Rare RuneGar x3
Random Magic or Rare RuneCem x3
Random Magic or Rare RuneNoc x3
Random Magic or Rare RuneCir x3


How to Craft Ancestral Mythic Uniques in Diablo 4 Vessel of Hatred & Season 6?

To begin crafting mythic uniques in Diablo 4, you’ll need to gather the necessary materials, including rare Runes and the Resplendent Spark, by exploring dungeons, defeating powerful bosses, and participating in various events.


To craft a random Mythic Unique, you can visit the Blacksmith and exchange 2 Resplendent Sparks and 50,000,000 D4 gold for a Mythic Unique Cache. This cache will contain a randomly selected Mythic Unique, which can be equipped as early as Level 35. The best part is that up to four of its affixes can roll as more powerful Greater Affixes, giving you an edge in combat.


If you're looking for a specific Mythic Unique item, you can head to the Jeweler and craft it using 2 Resplendent Sparks, multiple Runes, and 5,000 gold. The option to craft a specific Mythic Unique can be found in the Rune Crafting tab at the Jeweler. This method allows you to target the exact Mythic Unique you need in the Vessel of Hatred.



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